ChemicalBook > CAS DataBase List > 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine

3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine

Product Name
3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine
CAS No.
330819-85-7
Chemical Name
3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine
Synonyms
5H-Cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine, 6,7-dihydro-2-(methylthio)-;3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine
CBNumber
CB34482085
Molecular Formula
C10H11N3S2
Formula Weight
237.34
MOL File
330819-85-7.mol
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3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Property

storage temp. 
Store at -20°C
solubility 
DMF: 30mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2mg/mL; DMSO: 20mg/mL; PBS (pH 7.2): insolube
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21987
Product name
VU0029251
Packaging
1mg
Price
$26
Updated
2024/03/01
Cayman Chemical
Product number
21987
Product name
VU0029251
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
21987
Product name
VU0029251
Packaging
10mg
Price
$204
Updated
2024/03/01
Cayman Chemical
Product number
21987
Product name
VU0029251
Packaging
25mg
Price
$383
Updated
2024/03/01
AK Scientific
Product number
8099CD
Product name
10-Methylsulfanyl-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(12),2(6),8,10-tetraen-12-amine
Packaging
5mg
Price
$213
Updated
2021/12/16
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3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Chemical Properties,Usage,Production

Description

VU0029251 is a partial antagonist of metabotropic glutamate receptor 5 (mGluR5; Ki = 1.07 μM).1 It inhibits calcium mobilization induced by glutamate in HEK293 cell membranes expressing rat mGluR5 (IC50 = 1.7 μM).

References

1. Rodriguez, A.L., Grier, M.D., Jones, C.K., et al. Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity Mol. Pharmacol. 78(6),1105-1123(2010).

3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine Suppliers

China 7 Finland 1 United States 2 Global 10
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65

330819-85-7, 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amineRelated Search:

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  • 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine
  • 5H-Cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine, 6,7-dihydro-2-(methylthio)-
  • 330819-85-7